By Orly Skin

Science That Feels
Like Silk

1% GHK-Cu peptide serum in a silicone delivery base. One product. One protocol. Engineered for skin longevity by a practicing clinician.

Why Silicone?

The silicone base creates an optimized delivery vehicle for GHK-Cu, forming a breathable film that reduces transepidermal water loss, improves peptide absorption, and gives Peptide Potion its signature weightless, primer-finish texture.

1%
GHK-Cu Concentration
800+
Patients Treated
30ml
Full-Size Bottle

Ingredient Science

Every Molecule, Intentional

No filler ingredients, no 15-step routines. Peptide Potion is a single, precisely formulated serum built around clinically studied GHK-Cu at a concentration that respects the research.

GHK-Cu

Copper Tripeptide-1 — 1%

A naturally occurring peptide that supports repair signaling, collagen synthesis, and skin remodeling. Clinically studied across 60+ published papers for its role in skin longevity.

Silicone Delivery Base

Proprietary Blend

Creates a breathable, occlusive film that optimizes GHK-Cu delivery into the skin while leaving a weightless primer finish. Reduces water loss and improves spreadability.

Vitamin C Derivative

Stable Form

A stabilized vitamin C that supports brightness and even skin tone without the irritation or oxidation issues of pure ascorbic acid formulations.

Niacinamide

Vitamin B3

Supports skin barrier function, helps manage uneven tone, and works synergistically with GHK-Cu to support the skin's own repair processes.

Sodium Hyaluronate

Low Molecular Weight

A smaller-molecule form of hyaluronic acid that draws moisture into the skin, supporting plumpness and hydration without heaviness.

Bisabolol

Chamomile-Derived

A soothing botanical that calms reactive skin and supports the overall formulation's comfort on even sensitive skin types.

What to Expect

A 12-Week Protocol

Skin longevity is not overnight. Peptide Potion is designed for compounding results over consistent use.

Week 1

Immediate Comfort

Skin feels smoother and deeply hydrated. The silicone base provides all-day moisture retention and a silky-soft primer finish.

Week 4

Even-Toned & Resilient

Visible improvements in skin tone evenness. Skin feels more resilient and less reactive. The compounding effect begins.

Week 8

Improved Skin Quality

Noticeable improvement in overall skin quality. Fine lines appear softer. Texture becomes more refined.

Week 12

Full Protocol Results

Strongest improvements in skin texture, perceived firmness, and overall skin quality. This is when the protocol delivers its full potential.

The Clinician Behind the Formula

Dr. Shoham Berkowitz, DMD

Licensed Clinician • 800+ Patients • Fort Lauderdale, FL

After 11 years in clinical practice—graduating in the top 3% of her class—Dr. Berkowitz transitioned fully to medical aesthetics three years ago. She built a practice of over 800 patients entirely through word of mouth, guided by one principle:

“The best injectable is undetectable.”

Peptide Potion was born from her daily work with patients who wanted effective at-home skincare without the noise of a 15-product routine. One serum. One protocol. Built by a clinician who sees skin every single day.

@theaestheticsho • 13.1K followers

Verified Reviews

Customers Are Saying

Repair. Restore. Rebuild.

Reserve Your First Bottle

$135.00

Peptide Potion • Default Title

Free shipping on all pre-orders • 30-day satisfaction guarantee

Questions

Frequently Asked

Yes. The silicones used in Peptide Potion are non-comedogenic, dermatologically well-tolerated, and widely used in skincare and medical devices. They form a breathable film that optimizes peptide delivery while reducing transepidermal water loss. Silicone does not clog pores and is gentle enough for sensitive skin.

The silicone delivery base creates an occlusive microenvironment on the skin surface that slows evaporation and keeps the active ingredients—particularly GHK-Cu—in prolonged contact with the skin. This optimized contact time improves the delivery of peptides into the upper layers of the skin compared to water-based formulations that evaporate quickly.

GHK-Cu (Copper Tripeptide-1) is a naturally occurring peptide in the human body that declines with age. It is one of the most studied peptides in dermatological literature, with over 60 published papers examining its role in supporting skin repair signaling, collagen synthesis, and overall skin remodeling. At 1% concentration, Peptide Potion delivers a meaningful, research-supported dose.

All pre-orders ship beginning May 19, 2026. Orders are fulfilled in the sequence received. You will receive a shipping confirmation email with tracking details once your order is on its way.

Apply 2-3 drops to clean, dry skin morning and/or evening. The serum absorbs quickly and leaves a primer-like finish, so it works beautifully under makeup or sunscreen. Because of its silicone base, apply it after any water-based serums and before moisturizer or SPF.

Peptide Potion is formulated to be compatible with most skincare actives, including retinoids, AHAs, and vitamin C serums. Because GHK-Cu supports repair signaling, it pairs particularly well with ingredients that increase cell turnover. If you have specific concerns, consult your dermatologist.

Yes. You can subscribe to receive Peptide Potion monthly at $114.75/mo—a 15% savings from the one-time price of $135. Subscriptions are flexible: skip, pause, or cancel anytime with no penalties.

Peptide Potion was developed by Dr. Shoham Berkowitz, DMD—a licensed clinician with 11 years of clinical experience who now practices medical aesthetics full-time. The formulation is based on her direct work with over 800 patients and grounded in published peptide research.

We offer a 30-day satisfaction guarantee. If you are not satisfied with Peptide Potion for any reason, contact us within 30 days of receiving your order for a full refund. We stand behind the formulation because we know it works.